Prevalence of risk of deficiency and inadequacy of 25-hydroxyvitamin D in US children: NHANES 2003-2006 Journal Article

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Authors: Karalius, V. P.; Zinn, D.; Wu, J; Cao, G; Minutti, C.; Luke, A; Kramer, H; Durazo-Arvizu, R
Article Title: Prevalence of risk of deficiency and inadequacy of 25-hydroxyvitamin D in US children: NHANES 2003-2006
Abstract: Abstract Aim: To assess prevalence and population estimates of increased risk of 25-hydroxyvitamin D [25(OH)D] deficiency and inadequacy in US children based on the current Institute of Medicine Committee to Review Dietary References Intakes for Vitamin D and Calcium guidelines. Methods: The analysis was limited to a nationally representative sample of non-institutionalized US children and adolescents aged 6-18 years who participated in the National Health and Nutrition Examination Survey completed in 2003-2006 and had complete data on 25(OH)D measurements (n=2877). The 25(OH)D levels were adjusted for assay drift and prevalence, and population estimates of increased risk of 25(OH)D deficiency (20 ng/mL) were calculated. Results: Overall, 4.61% of children and adolescents are at increased risk of deficiency (population estimate 2.5 million) and 10.3% are at risk of inadequacy (population estimate 5.5 million) based on the Institute of Medicine guidelines. Conclusion: Approximately 10.3% of US children aged 6-18 years (population estimate 5.5 million) have 25(OH)D levels 16 ng/mL.
Journal Title: Journal of pediatric endocrinology metabolism : JPEM
Volume: 27
Issue: 5-6
ISSN: 2191-0251; 0334-018X
Publisher: Unknown  
Date Published: 2014
Start Page: 461
End Page: 466
Language: ENG
DOI/URL:

10.1515/jpem-2013-0246

10.1515/jpem-2013-0246
Notes: JID: 9508900; 1406-16-2 (Vitamin D); 64719-49-9 (25-hydroxyvitamin D); 2013/06/14 [received]; 2013/12/02 [accepted]; ppublish