Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic Clostridium difficile in asymptomatic carriers. Journal Article

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Authors: Donskey, CJ; Sunkesula, VC; Jencson, AL; Stone, ND; Gould, CV; McDonald, LC; Samore, M; Mayer, J; Pacheco, S; Sambol, S; Petrella, L; Terry, D; Gerding, DN
Article Title: Utility of a commercial PCR assay and a clinical prediction rule for detection of toxigenic Clostridium difficile in asymptomatic carriers.
Abstract: A commercial PCR assay of perirectal swab specimens detected 17 (68%) of 25 asymptomatic carriers of toxigenic Clostridium difficile, including 93% with skin and/or environmental contamination. A clinical prediction rule, followed by PCR screening, could be used to identify carriers at high risk of C. difficile shedding.
Journal Title: Journal of clinical microbiology
ISSN: 1098-660X; 0095-1137
Publisher: Unknown  
Date Published: 2014