Treatment of Clostridium Difficile Infections Journal Article

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Authors: Soriano, M. M.; Johnson, S
Article Title: Treatment of Clostridium Difficile Infections
Abstract: Vancomycin and metronidazole were historically considered equivalent therapies for the management of Clostridium difficile infections (CDI); however, recent data confirm more favorable outcomes with vancomycin. Fidaxomicin is a narrow spectrum antibiotic that has an advantage in reducing recurrence rates compared with vancomycin, possibly owing to its sparing effect on normal colonic microbiota. Data are limited for guiding management of CDI recurrences, particularly multiple recurrences. Several empiric approaches to manage these cases are reviewed.
Journal Title: Infectious disease clinics of North America
Volume: 29
Issue: 1
ISSN: 1557-9824; 0891-5520
Publisher: Unknown  
Date Published: 2015
Start Page: 93
End Page: 108
Language: ENG
DOI/URL:

S0891-5520(14)00082-8
Notes: LR: 20150113; CI: Published by Elsevier Inc.; JID: 8804508; OTO: NOTNLM; aheadofprint