A Tapered-Pulsed Fidaxomicin Regimen following Treatment in Patients with Multiple Clostridioides difficile Infection Recurrences. Journal Article


Authors: Skinner, AM; Tan, X; Sirbu, BD; Danziger, LH; Gerding, DN; Johnson, S
Article Title: A Tapered-Pulsed Fidaxomicin Regimen following Treatment in Patients with Multiple Clostridioides difficile Infection Recurrences.
Abstract: We treated 46 patients with multiple recurrent Clostridioides difficile infections (mrCDI) using a tapered-pulsed (T-P) fidaxomicin regimen, the majority of whom failed prior T-P vancomycin treatment. Sustained clinical response rates at 30 and 90 days were 74% (34/46) and 61% (28/46). T-P fidaxomicin shows promise for management of mrCDI.
Journal Title: Clinical Infectious Diseases
ISSN: 1058-4838
Publisher: Unknown  
Date Published: 2021