Late onset CNS immune reconstitution inflammatory syndrome in an immunocompetent patient Journal Article

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Authors: Hornik, A.; Rodriguez-Porcel, F.; Wallery, S.; Flaster, M.; Lee, J. M.; Biller, J
Article Title: Late onset CNS immune reconstitution inflammatory syndrome in an immunocompetent patient
Abstract: Immune reconstitution inflammatory syndrome (IRIS) refers to the presence of paradoxical clinical deterioration attributable to immune system recovery during highly active antiretroviral therapy (HAART). We present an immunocompetent patient with multifocal leukoencephalopathy on HAART, with central nervous system (CNS) IRIS pathology of unknown infectious etiology. CNS IRIS pathology should be suspected in patients on longstanding HAART without immune reconstitution, presenting with unexplained leukoencephalopathy.
Journal Title: Frontiers in neurology
Volume: 4
ISSN: 1664-2295; 1664-2295
Publisher: Unknown  
Journal Place: Switzerland
Date Published: 2013
Start Page: 12
Language: eng
DOI/URL:

10.3389/fneur.2013.00012

10.3389/fneur.2013.00012
Notes: ID: 13008; LR: 20130415; JID: 101546899; OID: NLM: PMC3578199; OTO: NOTNLM; 2013/01/16 [received]; 2013/02/02 [accepted]; 2013/02/21 [epublish]; ppublish