Expanding the Morphologic Spectrum of Adult Biphasic Renal TumorsMixed Epithelial and Stromal Tumor of the Kidney With Focal Papillary Renal Cell Carcinoma: Case Report and Review of the Literature Journal Article

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Authors: Mudaliar, K. M.; Mehta, V; Gupta, G. N.; Picken, M. M.
Article Title: Expanding the Morphologic Spectrum of Adult Biphasic Renal TumorsMixed Epithelial and Stromal Tumor of the Kidney With Focal Papillary Renal Cell Carcinoma: Case Report and Review of the Literature
Abstract: Mixed epithelial and stromal tumor (MEST) is a distinctive adult biphasic neoplasm of the kidney characterized by the presence of solid and cystic areas composed of spindled stroma and epithelium lining tubules and cystic spaces respectively. Most MESTs are benign although sarcomatous transformation has rarely been reported. It has not been clearly established whether the epithelial component represents entrapped tubules or constitutes a true neoplastic component. We report an unusual case of a biphasic tumor of the kidney with a benign stroma and a focal component of papillary carcinoma arising in one of the cysts and discuss its pathogenesis.
Journal Title: International Journal of Surgical Pathology
Volume: 22
Issue: 3
ISSN: 1940-2465
Publisher: Unknown  
Date Published: 2014
Start Page: 266
End Page: 271
Language: ENG
DOI/URL:

10.1177/1066896913488823
Notes: JID: 9314927; 0 (Tumor Markers, Biological); OTO: NOTNLM; 2013/05/27 [aheadofprint]; ppublish