Penile Paget's Disease: A Case Report and Review of the Literature. Journal Article


Authors: Flanigan, RC; Dornbier, R; Quek, ML; Woods, M; Gorbonos, A; Gupta, G; Harkenrider, MM; Solanki, A; Badami, A; Henry, E; Berg, S; Bova, D; Barkan, GA; Picken, MM
Article Title: Penile Paget's Disease: A Case Report and Review of the Literature.
Abstract: Extramammary Paget's Disease (EMPD) is a rare cutaneous, slow growing, intraepithelial adenocarcinoma that can be either primary (intraepithelial arising within the epidermis) or secondary (intraepithelial spread of a visceral carcinoma). Here we present the case of a 63-year-old male with EMPD of the glans penis stemming from underlying urothelial carcinoma. Our treatment decision elected for management with chemotherapy and local treatment with radiation therapy. Subsequent, review of the literature demonstrated a rare disease with a variety of underlying malignancies causing this secondary pathology. Caregivers should be aware of the association of Paget's disease and urothelial cancer and should have a high index of suspicion that erythematous penile lesions may represent Paget's disease and that penile biopsies should be performed early in this setting.
Journal Title: ARCHIVES OF NEPHROLOGY AND UROLOGY
Publisher: Unknown  
Date Published: 2020
LUC Authors
  1. Guliz Akdas Barkan
    67 Barkan
  2. Gopal Gupta
    99 Gupta
  3. Elizabeth Henry
    15 Henry
  4. Maria M. Picken
    74 Picken
  5. Marcus Quek
    69 Quek
  6. Davide Bova
    15 Bova
  7. Abhishek Solanki
    72 Solanki
  8. Stephanie Berg
    17 Berg
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