Surgical Reintervention Rate after Prostatic Urethral Lift: Systematic Review and Meta-Analysis Involving over 2,000 Patients. Journal Article

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Authors: Miller, LE; Chughtai, B; Dornbier, RA; McVary, KT
Article Title: Surgical Reintervention Rate after Prostatic Urethral Lift: Systematic Review and Meta-Analysis Involving over 2,000 Patients.
Abstract: PURPOSE: The surgical reintervention rate after prostatic urethral lift (PUL) is not well characterized, but has been estimated at 2-3%/yr. We performed a systematic review and meta-analysis to determine the surgical reintervention rate after PUL. MATERIALS AND METHODS: We systematically searched Medline, Embase, and the Cochrane Central Register of Controlled Trials for studies of men treated with PUL reporting at least 1 year of maximum follow-up data. We performed a random effects meta-analysis to estimate the annual rate of surgical reintervention after PUL, including those performed for lower urinary tract symptoms (LUTS) or involving device explant, additions, or replacement. The robustness of the meta-analysis conclusions was evaluated in a one-study removed analysis and heterogeneity was investigated with a subgroup analysis. RESULTS: In 11 studies (2,016 patients), 153 surgical reinterventions were performed, among which transurethral resection of the prostate/laser (51.0%), repeat PUL (32.7%), and device explant (19.6%) were most common. The annual rate of surgical reintervention was 6.0%/yr (95% CI: 3.0%-8.9%). These results were not significantly influenced by any single study. The annual rate of surgical intervention was significantly influenced by the mean duration of patient follow-up. Surgical reintervention rates were 4.3%/yr in studies with =1 year mean follow-up, 10.7%/yr in studies with >1 year to 3 years mean follow-up, and 5.8%/yr in a single study with >3 years mean follow-up (p=0.04). CONCLUSIONS: The surgical reintervention rate with PUL is 6.0%/yr and is higher in studies with longer follow-up durations.
Journal Title: The Journal of urology
ISSN: 1527-3792; 0022-5347
Publisher: Unknown  
Date Published: 2020