Leptomeningeal metastasis from solid tumors. Journal Article

Authors: Thakkar, JP; Kumthekar, P; Dixit, KS; Stupp, R; Lukas, RV
Article Title: Leptomeningeal metastasis from solid tumors.
Abstract: Central nervous system (CNS) metastasis from systemic cancers can involve the brain parenchyma, leptomeninges (pia, subarachnoid space and arachnoid mater), and dura. Leptomeningeal metastases (LM), also known by different terms including neoplastic meningitis and carcinomatous meningitis, occur in both solid tumors and hematologic malignancies. This review will focus exclusively on LM arising from solid tumors with a goal of providing the reader an understanding of the epidemiology, pathophysiology, clinical presentation, prognostication, current management and future directions.
Journal Title: Journal of the neurological sciences
ISSN: 1878-5883; 0022-510X
Publisher: Elsevier Inc  
Date Published: 2020
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