Characterization and spontaneous induction of urinary tract prophages. Journal Article

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Authors: Brassil, B; Mores, CR; Wolfe, AJ; Putonti, C
Article Title: Characterization and spontaneous induction of urinary tract prophages.
Abstract: is an often overlooked and understudied emerging pathogen inhabiting many areas of the human body. Through our sequencing of strains isolated from the female bladder microbiota, we detected numerous prophage sequences. Bioinformatic analysis of these sequences identified 17 distinct groups of prophages. The majority of these phages exhibit no sequence homology to previously characterized temperate or virulent phage sequences, indicating an unexplored diversity of phages. By culturing these bacterial isolates, we confirmed that the prophages of five of these groups are capable of induction. One of these putative phages was imaged, the first such evidence of an . virus-like particle; it exhibits morphological characteristics of siphoviruses.
Journal Title: The Journal of general virology
ISSN: 1465-2099; 0022-1317
Publisher: Unknown  
Date Published: 2020