miRNA degradation in the mammalian brain. Journal Article

Authors: Kim, CK; Pak, TR
Article Title: miRNA degradation in the mammalian brain.
Abstract: miRNAs are short, noncoding RNAs that are evolutionarily conserved across many different species. miRNA regulation of gene expression, specifically in the context of the mammalian brain, has been well characterized; however, the regulation of miRNA degradation is still the focus of ongoing research. This review will focus on recent findings concerning the cellular mechanisms that govern miRNA degradation with an emphasis on TDMD (target mediated miRNA degradation) and how this phenomenon is uniquely poised to maintain homeostasis in neuronal systems.
Journal Title: American journal of physiology. Cell physiology
Publisher: Unknown  
Date Published: 2020