Major publications in the critical care pharmacotherapy literature in 2015. Journal Article


Authors: Wong, A; Erdman, M; Hammond, DA; Holt, T; Holzhausen, JM; Horng, M; Huang, LL; Jarvis, J; Kram, B; Kram, S; Lesch, C; Mercer, J; Rech, MA; Rivosecchi, R; Stump, B; Teevan, C; Day, S
Article Title: Major publications in the critical care pharmacotherapy literature in 2015.
Abstract: PURPOSE: Recently published practice guidelines and research reports on pharmacotherapy in critical care patient populations are summarized. SUMMARY: The Critical Care Pharmacotherapy Literature Update (CCPLU) Group is composed of over 50 experienced critical care pharmacists who evaluate 31 peer-reviewed journals monthly to identify literature pertaining to pharmacotherapy in critical care populations. Articles are chosen for summarization in a monthly CCPLU Group publication on the basis of applicability and relevance to clinical practice and strength of study design. From January to December 2015, a total of 121 articles were summarized; of these, 3 articles presenting clinical practice guidelines and 12 articles presenting original research findings were objectively selected for inclusion in this review based on their potential to change or reinforce current evidence-based practice. The reviewed guidelines address the management of intracranial hemorrhage (ICH), adult advanced cardiac life support (ACLS) and post-cardiac arrest care, and the management of supraventricular tachycardia (SVT). The reviewed research reports address topics such as nutrition in critically ill adults, administration of ß-lactams for severe sepsis, anticoagulant selection in the context of continuous renal replacement therapy, early goal-directed therapy in septic shock, magnesium use for neuroprotection in acute stroke, and progesterone use in patients with traumatic brain injury. CONCLUSION: Important recent additions to the critical care pharmacy literature include updated joint clinical practice guidelines on the management of spontaneous ICH, ACLS, and SVT.
Journal Title: American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
ISSN: 1535-2900; 1079-2082
Publisher: Unknown  
Date Published: 2017