Venous thromboembolism after diaphragm pacing in amyotrophic lateral sclerosis. Journal Article


Authors: Rezania, K; Gottlieb, O; Guralnick, A; Prachand, V; Sweitzer, BJ; Vigneswaran, W; White, SR; Roos, RP
Article Title: Venous thromboembolism after diaphragm pacing in amyotrophic lateral sclerosis.
Abstract: INTRODUCTION: Patients with amyotrophic lateral sclerosis (ALS) are prone to venous thromboembolism (VTE) and secondary complications. Because there is an increased incidence of VTE after surgical procedures, placement of a Diaphragm Pacing System (DPS) in ALS patients as treatment for respiratory muscle weakness could potentially increase the incidence of VTE, especially in patients with limited mobility. METHODS: We implanted a DPS in 10 ALS patients who met the criteria for this procedure. They underwent a preoperative evaluation as recommended by the guidelines. RESULTS: We report 2 patients with no symptoms of deep vein thrombosis (DVT) before the surgical procedure who then developed perioperative VTE. CONCLUSIONS: These patients highlight the need to consider preoperative screening for DVT and postoperative thromboprophylaxis in high-risk ALS patients who undergo DPS placement.
Journal Title: Muscle nerve
ISSN: 1097-4598; 0148-639X
Publisher: Unknown  
Date Published: 2014