The influence of (18)flourodeoxyglucose positron emission tomography on the management of gastroesophageal junction carcinoma. Journal Article

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Authors: Smith, J. W.; Moreira, J.; Abood, G; Aranha, G. V.; Nagda, S.; Wagner, R. H.; Shoup, M.
Article Title: The influence of (18)flourodeoxyglucose positron emission tomography on the management of gastroesophageal junction carcinoma.
Abstract: BACKGROUND: The influence of positron emission tomography (PET) scanning with flourodeoxyglucose (FDG) on decision making for the treatment of patients with esophagogastric junction (EGJ) carcinoma is unclear as is the utility of the maximum standardized uptake value (SUV) as a prognostic indicator. METHODS: This study was a retrospective review of EGJ carcinoma cases at a single institution during a 5-year period. RESULTS: FDG-PET altered treatment in 13 of 64 patients (20%). Of these, 21 patients had PET scans before and after undergoing neoadjuvant chemoradiation (CRT) as well as surgery. Patients who had a decrease in SUV gt;50% had a 12-month disease-free survival advantage over patients a decrease in SUV 50% decrease in SUV after CRT is associated with an improved prognosis.
Journal Title: American Journal of Surgery
Volume: 197
Issue: 3
ISSN: 1879-1883; 0002-9610
Publisher: Elsevier Inc  
Journal Place: United States
Date Published: 2009
Start Page: 308
End Page: 312
Language: English
Notes: ID: 4879; Record Owner: From MEDLINE, a database of the U.S. National Library of Medicine.; Status: MEDLINE; Publishing Model: Journal available in: Print Citation processed from: Internet; NLM Journal Code: 3z4, 0370473; CAS Registry/EC Number/Name of Substance: 0 (Radiopharmaceuticals). 63503-12-8 (Fluorodeoxyglucose F18).; Entry Date: 20090401 poster Presentation at the 49th Annual Meeting for Surgery of the Alimentary Tract, May 17-21, 2008, San Diego, CA