Genome sequences and annotation of two urinary isolates of E. coli Journal Article


Authors: Price, T. K.; Mehrtash, A.; Kalesinskas, L; Malki, K; Hilt, E. E.; Putonti, C; Wolfe, A. J.
Article Title: Genome sequences and annotation of two urinary isolates of E. coli
Abstract: The genus Escherichia includes pathogens and commensals. Bladder infections (cystitis) result most often from colonization of the bladder by uropathogenic E. coli strains. In contrast, a poorly defined condition called asymptomatic bacteriuria results from colonization of the bladder with E. coli strains without symptoms. As part of an on-going attempt to identify and characterize the newly discovered female urinary microbiota, we report the genome sequences and annotation of two urinary isolates of E. coli: one (E78) was isolated from a female patient who self-reported cystitis; the other (E75) was isolated from a female patient who reported that she did not have symptoms of cystitis. Whereas strain E75 is most closely related to an avian extraintestinal pathogen, strain E78 is a member of a clade that includes extraintestinal strains often found in the human bladder. Both genomes are uncommonly rich in prophages.
Journal Title: Standards in genomic sciences
Volume: 11
ISSN: 1944-3277
Publisher: Unknown  
Journal Place: England
Date Published: 2016
Start Page: 79
Language: eng
DOI/URL:
Notes: LR: 20170220; GR: R21 DK097435/DK/NIDDK NIH HHS/United States; JID: 101530505; OTO: NOTNLM; 2016/05/13 [received]; 2016/10/04 [accepted]; epublish