Treatment of locally advanced parotid malignancies with parotidectomy and temporal bone resection Journal Article

Local Library Link: Find It @ Loyola

Authors: Martin, J. R.; Filip, P.; Thorpe, E. J.; Leonetti, J. P.
Article Title: Treatment of locally advanced parotid malignancies with parotidectomy and temporal bone resection
Abstract: PURPOSE: In this study we review our institution's experience and outcomes with temporal bone resection and parotidectomy in the treatment of advanced parotid malignancies. METHODS: Patients undergoing lateral temporal bone resection and parotidectomy from 2007-2013 were identified in the EPIC electronic medical record. Primary tumor location, staging, surgical procedure, and patient demographic and outcome data were collected retrospectively. RESULTS: Fifteen patients underwent combined temporal bone resection and parotidectomy for parotid malignancy. Carcinoma ex-pleomorphic and squamous cell carcinoma were the most common pathologies. Two year disease free survival was 40%. Distant metastases were the most common site of disease recurrence. Only nodal disease was predictive of reduced disease free survival, though pre-operative facial paralysis showed a trend towards significance. Margin status and operating for recurrent tumor did not influence outcome in our series. CONCLUSION: Local and regional tumor controls are attainable with combined skull base approaches to advanced parotid malignancies. Unfortunately these cases have a high rate of distant recurrence despite negative margins and local control.
Journal Title: American Journal of Otolaryngology
ISSN: 1532-818X; 0196-0709
Publisher: Unknown  
Journal Place: United States
Date Published: 2017
Language: eng
DOI/URL:

S0196-0709(16)30274-5
Notes: LR: 20170509; CI: Copyright (c) 2017; JID: 8000029; 2016/08/30 [received]; 2017/03/06 [revised]; 2017/03/31 [accepted]; aheadofprint