Bivalirudin and transcatheter aortic valve replacement: a cautionary tale Journal Article

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Authors: Sangani, N. K.; Greason, K. L.; Torres, N. E.; Suri, R. M.; Mathew, V
Article Title: Bivalirudin and transcatheter aortic valve replacement: a cautionary tale
Abstract: Bivalirudin is an accepted alternative to heparin for anticoagulation during select cardiac procedures. Its use has not been well described during transcatheter aortic valve replacement. Herein is the report of a transcatheter valve replacement case that was complicated by catastrophe and need for emergent cardiopulmonary bypass. A successful outcome was achieved. However, the inability to rapidly reverse the anticoagulation effect of bivalirudin proved troublesome, and that provides for a cautionary tale about its use during transcatheter valve replacement.
Journal Title: The Annals of Thoracic Surgery
Volume: 98
Issue: 6
ISSN: 1552-6259; 0003-4975
Publisher: Unknown  
Journal Place: Netherlands
Date Published: 2014
Start Page: 2214
End Page: 2215
Language: eng
DOI/URL:

10.1016/j.athoracsur.2014.01.074
Notes: LR: 20161125; CI: Copyright (c) 2014; JID: 15030100R; 0 (Anticoagulants); 0 (Hirudins); 0 (Peptide Fragments); 0 (Recombinant Proteins); TN9BEX005G (bivalirudin); 2013/12/07 [received]; 2013/12/07 [revised]; 2014/01/14 [accepted]; ppublish