Authors: | Payne, A. J.; Kaja, S.; Sabates, N. R.; Koulen, P. |
Article Title: | A case for neuroprotection in ophthalmology: developments in translational research |
Abstract: | Cellular aging occurs by the lifelong accumulation of oxidative damage leading to neuronal apoptosis, termed 'neurodegeneration', and the functional deficits of aging. Loss of visual function is one of the most important quality of life measures for older adults. We discuss recent clinical and laboratory advances in the neuroprotective treatment of the aging eye with particular emphasis on the three major ocular neurodegenerative conditions: glaucoma, age-related macular degeneration (AMD), and diabetic retinopathy (DR). |
Journal Title: | Missouri medicine |
Volume: | 110 |
Issue: | 5 |
ISSN: | 0026-6620; 0026-6620 |
Publisher: | Unknown |
Journal Place: | United States |
Date Published: | 2013 |
Start Page: | 429 |
End Page: | 436 |
Language: | ENG |
Notes: | LR: 20161019; GR: P01 AG022550/AG/NIA NIH HHS/United States; GR: P01 AG027956/AG/NIA NIH HHS/United States; GR: AG010485/AG/NIA NIH HHS/United States; GR: R01 EY014227/EY/NEI NIH HHS/United States; GR: AG022550/AG/NIA NIH HHS/United States; GR: P01 AG010485/AG/NIA NIH HHS/United States; GR: EY014227/EY/NEI NIH HHS/United States; GR: R01 EY022774/EY/NEI NIH HHS/United States; GR: EY022774/EY/NEI NIH HHS/United States; GR: RR022570/RR/NCRR NIH HHS/United States; GR: AG027956/AG/NIA NIH HHS/United States; GR: S10 RR027093/RR/NCRR NIH HHS/United States; GR: S10 RR022570/RR/NCRR NIH HHS/United States; GR: RR027093/RR/NCRR NIH HHS/United States; JID: 0400744; 0 (Neuroprotective Agents); NIHMS566242; OID: NLM: NIHMS566242; OID: NLM: PMC3973483; ppublish |