Early Recognition and Treatment of Sepsis After the Addition of Lactate to the Laboratory's Critical Result Call List Journal Article

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Authors: Kuttab, H. I.; Sterk, E; Rech, M. A.; Nghiem, T; Bahar, B.; Kahn, S
Article Title: Early Recognition and Treatment of Sepsis After the Addition of Lactate to the Laboratory's Critical Result Call List
Abstract: PURPOSE: Screening of patients with sepsis is needed to increase recognition and allow for earlier interventions. There is no consensus on whether the addition of lactate to the critical result laboratory's call list should be a standard practice. MATERIALS AND METHODS: This was a retrospective cohort study that compared management and outcomes of patients with sepsis having lactate >/=4 mmol/L before (group 1) and after (group 2) the addition of a critical result threshold of lactate of >/=4 mmol/L to the critical result laboratory's call list and its effects on time to antibiotics and intravenous fluids (IVFs). RESULTS: One hundred twenty-one patients were included. Lactate was higher in group 1 (7.0 +/- 4.3 vs 5.6 +/- 2.0, P = 0.03). More patients in group 2 received hydrocortisone (1.9% vs 22.4%, P = .001). Hospital mortality, 30-day mortality, and 90-day mortality were significantly lower in group 2 (59.3% vs 32.8%, P = .003; 68.5% vs 37.3%, P
Journal Title: Journal of intensive care medicine
ISSN: 1525-1489; 0885-0666
Publisher: Unknown  
Date Published: 2016