Abstract: |
Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiac disorder with a prevlance of 1:500 in adults. It is characterized by myocardial hypertrophy in the absence of significant hemodynamic stress.1 From a genetic standpoint, the disease is most commonly associated with autosomal dominant mutations of sarcomeric genes.2,3 The clinical course of HCM varies with heterogeneous progression to sudden cardiac death at early stages to 'burned out' myocardial disease with systolic heart failure and atrial fibrillation (AF) with cerebrovascular embolic complications at later stages.4 This article is protected by copyright. All rights reserved. |