"Right place at the right time" impacts outcomes for acute intestinal obstruction Journal Article


Authors: Kothari, A. N.; Liles, J. L.; Holmes, C. J.; Zapf, M. A.; Blackwell, R. H.; Kliethermes, S; Kuo, P. C.; Luchette, F. A.
Article Title: "Right place at the right time" impacts outcomes for acute intestinal obstruction
Abstract: BACKGROUND: The purpose of this study was to measure how the duration of nonoperative intervention for intestinal obstruction impacted patient outcomes and whether hospital characteristics influenced the timing of operative intervention. METHODS: The State Inpatient Database (Florida) of the Health Care Utilization Project and the Annual Survey database of the American Hospital Association were linked from 2006 to 2011. Included were patients >/=18 years of age with a primary diagnosis of intestinal obstruction. Patient factors included age, sex, socioeconomic factors, and comorbid conditions. RESULTS: A total of 116,195 patients met our inclusion criteria, and 43,079 underwent operative intervention (37.1%). Patients who required operative correction of the intestinal obstruction after the fifth day of hospitalization, compared with patients who underwent an operation on the day of admission, had increases in mortality (6.1% vs 1.8%, P .001), complication rates (15.4% vs 4.0%, P .001), and postoperative hospital stay (9 vs 5 days, P .001). Patients cared for at a large teaching facility (with surgery residents) had increased odds of early operative intervention by 23% (odds ratio 1.23, [1.20-1.28]), whereas patients at low-volume hospitals had decreased odds of early intervention (odds ratio 0.88, [0.73-0.91]). CONCLUSION: Initial nonoperative treatment in patients with uncomplicated intestinal obstruction is an important strategy, but the odds of having an adverse event increase as intestinal obstruction is delayed. Importantly, the presence of surgery residents and increasing bed size are hospital characteristics associated with earlier operative intervention, suggesting a quality benefit for care at large teaching hospitals.
Journal Title: Surgery
Volume: 158
Issue: 4
ISSN: 1532-7361; 0039-6060
Publisher: Elsevier Inc  
Journal Place: United States
Date Published: 2015
Start Page: 1116
End Page: 25; discussion 1125-7
Language: eng
DOI/URL:
Notes: LR: 20151106; CI: Copyright (c) 2015; GR: T32 GM008750/GM/NIGMS NIH HHS/United States; JID: 0417347; 2015/02/20 [received]; 2015/06/07 [revised]; 2015/06/24 [accepted]; 2015/08/01 [aheadofprint]; ppublish