Osteomesopyknosis: A Case Report and Review of Sclerosing Bone Disorders Journal Article

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Authors: Yao, A. L.; Camacho, P. M.
Article Title: Osteomesopyknosis: A Case Report and Review of Sclerosing Bone Disorders
Abstract: Objective: The paper presents a case of osteomesopyknosis, a non-malignant sclerosing bone dysplasia of the axial skeleton with an unknown cause and unknown prevalence.Methods: We studied a 49-year-old woman who suffered from back and pelvic pain. Her history was obtained, physical examination performed, and laboratory results and imaging diagnostics done and studied to describe her and her disease.Results: A 49-year-old, perimenopausal woman suffered excruciating, intermittent, dull back and pelvic pain over the course of a year and a half. Non-malignant blastic bone lesions along her spine and pelvis were discovered on CT scan coincidentally, confirmed by MRI and bone scans. Other metabolic/endocrine conditions were ruled out. Her son also has similar symptoms and similar images were seen on his vertebrae via MRI.Conclusion: Osteomesopyknosis is a rare, autosomal dominant condition characterized by non-malignant osteosclerosis restricted to the axial skeleton [1-5]. The disease may produce chronic low-grade back pain in the thoracic and lumbar regions [3]. The patient and her son are diagnosed to have osteomesopyknosis.
Journal Title: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
ISSN: 1934-2403; 1530-891X
Publisher: Unknown  
Date Published: 2014
Start Page: 1
End Page: 14
Language: ENG
DOI/URL:

10.4158/EP13352.CR
Notes: JID: 9607439; OTO: NOTNLM; aheadofprint; SO: Endocr Pract. 2014 Mar 18:1-14.
LUC Authors
  1. Pauline Camacho
    24 Camacho
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