Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study Journal Article

Local Library Link: Find It @ Loyola

Authors: O'Brien, L. M.; Bullough, A S; Owusu, J. T.; Tremblay, K. A.; Brincat, C. A.; Chames, M. C.; Kalbfleisch, J. D.; Chervin, R. D.
Article Title: Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study
Abstract: OBJECTIVE: This study aimed to prospectively examine the impact of chronic vs pregnancy-onset habitual snoring on gestational hypertension, preeclampsia, and gestational diabetes. STUDY DESIGN: Third-trimester pregnant women were recruited from a large, tertiary medical center from March 2007 through December 2010 and screened for the presence and duration of habitual snoring, as a known marker for sleep-disordered breathing. Clinical diagnoses of gestational hypertension, preeclampsia, and gestational diabetes were obtained. RESULTS: Of 1719 pregnant women, 34% reported snoring, with 25% reporting pregnancy-onset snoring. After adjusting for confounders, pregnancy-onset, but not chronic, snoring was independently associated with gestational hypertension (odds ratio, 2.36; 95% confidence interval, 1.48-3.77; P .001) and preeclampsia (odds ratio, 1.59; 95% confidence interval, 1.06-2.37; P = .024) but not gestational diabetes. CONCLUSION: New-onset snoring during pregnancy is a strong risk factor for gestational hypertension and preeclampsia. In view of the significant morbidity and health care costs associated with hypertensive diseases of pregnancy, simple screening of pregnant women may have clinical utility.
Journal Title: American Journal of Obstetrics and Gynecology
Volume: 207
Issue: 6
ISSN: 1097-6868; 0002-9378
Publisher: Unknown  
Journal Place: United States
Date Published: 2012
Start Page: 487.e1
End Page: 487.e9
Language: eng
DOI/URL:

10.1016/j.ajog.2012.08.034

10.1016/j.ajog.2012.08.034
Notes: LR: 20130717; CI: Copyright (c) 2012; GR: K23 HL095739/HL/NHLBI NIH HHS/United States; GR: R21 HL087819/HL/NHLBI NIH HHS/United States; GR: R21 HL089918/HL/NHLBI NIH HHS/United States; GR: UL1 RR024986/RR/NCRR NIH HHS/United States; JID: 0370476; CIN: Am J Obstet Gynecol. 2013 Jun;208(6):507. PMID: 23333545; CIN: Am J Obstet Gynecol. 2013 Jun;208(6):507-8. PMID: 23333550; NIHMS406762; OID: NLM: NIHMS406762 [Available on 12/01/13]; OID: NLM: PMC3505221 [Available on 12/01/13]; PMCR: 2013/12/01 00:00; 2012/05/06 [received]; 2012/07/20 [revised]; 2012/08/27 [accepted]; 2012/09/07 [aheadofprint]; ppublish