Authors: |
Morales-Vidal, S.; Schneck, M. J.; Flaster, M.; Biller, J |
Article Title: |
Direct thrombin inhibitors and factor Xa inhibitors in patients with cerebrovascular disease |
Abstract: |
Stroke is a leading cause of cardiovascular morbidity and mortality worldwide. Approximately, 795,000 strokes occur in the USA each year, 610,000 of which are first events, and 185,000 of which are recurrent events. Of all strokes, 87% are ischemic strokes. Novel anticoagulants serve as an alternative antithrombotic intervention in patients with ischemic cerebrovascular disease. This paper reviews the role of the novel anticoagulants, dabigatran, rivaroxaban and apixaban, in stroke prevention among patients with nonvalvular atrial fibrillation. |
Journal Title: |
Expert Review of Neurotherapeutics
|
Volume: |
12 |
Issue: |
2 |
ISSN: |
1744-8360 |
Publisher: |
Unknown
|
Journal Place: |
England |
Date Published: |
2012 |
Start Page: |
179 |
End Page: |
189 |
Language: |
English |
DOI/URL: |
|
Notes: |
ID: 12356; Record Owner: From MEDLINE, a database of the U.S. National Library of Medicine.; Status: MEDLINE; [Review]; Publishing Model: Journal available in: Print Citation processed from: Internet; NLM Journal Code: 101129944; CAS Registry/EC Number/Name of Substance: 0 (Antithrombins). 0 (Benzimidazoles). 0 (Morpholines). 0 (N-((2-(((4-(aminoiminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)-N-2-pyridinyl-beta-alanine). 0 (Pyrazoles). 0 (Pyridones). 0 (Thiophenes). 0 (apixaban). 0 (rivaroxaban). 107-95-9 (beta-Alanine). EC 3-4-21-6 (Factor Xa).; Entry Date: 20120622 |