The Bacillus subtilis endospore: assembly and functions of the multilayered coat Journal Article

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Authors: McKenney, P. T.; Driks, A; Eichenberger, P
Article Title: The Bacillus subtilis endospore: assembly and functions of the multilayered coat
Abstract: Sporulation in Bacillus subtilis involves an asymmetric cell division followed by differentiation into two cell types, the endospore and the mother cell. The endospore coat is a multilayered shell that protects the bacterial genome during stress conditions and is composed of dozens of proteins. Recently, fluorescence microscopy coupled with high-resolution image analysis has been applied to the dynamic process of coat assembly and has shown that the coat is organized into at least four distinct layers. In this Review, we provide a brief summary of B. subtilis sporulation, describe the function of the spore surface layers and discuss the recent progress that has improved our understanding of the structure of the endospore coat and the mechanisms of coat assembly.
Journal Title: Nature reviews.Microbiology
Volume: 11
Issue: 1
ISSN: 1740-1534; 1740-1526
Publisher: Unknown  
Journal Place: England
Date Published: 2013
Start Page: 33
End Page: 44
Language: eng
DOI/URL:

10.1038/nrmicro2921

10.1038/nrmicro2921
Notes: GR: GM081571/GM/NIGMS NIH HHS/United States; GR: R01AI093493/AI/NIAID NIH HHS/United States; GR: R21AI097934/AI/NIAID NIH HHS/United States; JID: 101190261; 0 (Bacterial Proteins); 0 (spore-specific proteins, Bacillus); 2012/12/03 [aheadofprint]; ppublish