Breaking the LSD1/KDM1A addiction: therapeutic targeting of the epigenetic modifier in AML Journal Article

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Authors: Lokken, A. A.; Zeleznik-Le, N. J.
Article Title: Breaking the LSD1/KDM1A addiction: therapeutic targeting of the epigenetic modifier in AML
Abstract: KDM1A/LSD1, a histone H3K4/K9 demethylase and epigenetic regulator with roles in both gene activation and repression, has increased expression in multiple cancer types. Harris et al., in this issue of Cancer Cell, and Schenk et al. show that KDM1A may be a viable therapeutic target in treating AML.
Journal Title: Cancer cell
Volume: 21
Issue: 4
ISSN: 1878-3686; 1535-6108
Publisher: Elsevier Inc  
Journal Place: United States
Date Published: 2012
Start Page: 451
End Page: 453
Language: eng
DOI/URL:

10.1016/j.ccr.2012.03.027

10.1016/j.ccr.2012.03.027
Notes: CI: Copyright (c) 2012; JID: 101130617; CON: Cancer Cell. 2012 Apr 17;21(4):473-87. PMID: 22464800; ppublish