Race and the insulin resistance syndrome Journal Article

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Authors: Kramer, H; Dugas, L; Rosas, S. E.
Article Title: Race and the insulin resistance syndrome
Abstract: Type 2 diabetes remains an important cause of morbidity and mortality. The metabolic syndrome affects 25% of the adult US population based on the Third Report of the Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults from the National Cholesterol Education Program. Knowledge on the impact of obesity on metabolic health parameters has increased greatly over the past decade. This review discusses the limitations of the National Cholesterol Education Program metabolic syndrome definition and the racial disparities in the clinical presentation of the insulin resistance syndrome. We also examine the current literature with particular emphasis on albuminuria, nonalcoholic fatty liver disease, and intramyocellular lipid content. This review explores potential environmental and genetic reasons for differences in the manifestation of insulin resistance across racial/ethnic groups and highlights several promising areas for further study.
Journal Title: Seminars in nephrology
Volume: 33
Issue: 5
ISSN: 1558-4488; 0270-9295
Publisher: Elsevier Inc  
Journal Place: United States
Date Published: 2013
Start Page: 457
End Page: 467
Language: eng
DOI/URL:

10.1016/j.semnephrol.2013.07.007

10.1016/j.semnephrol.2013.07.007
Notes: CI: (c) 2013; JID: 8110298; OTO: NOTNLM; ppublish