Potential of targeting TGF-beta for organ transplant patients Journal Article

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Authors: Iwashima, M; Love, R.
Article Title: Potential of targeting TGF-beta for organ transplant patients
Abstract: TGF-beta was originally considered as an immunoregulatory cytokine, but accumulating data demonstrate that it also plays a critical role in development of effector immunity. Since TGF- beta has a potent ability to alter immune responses, modulation of the TGF-beta pathway for treatment of transplantation patients could be effective if carried out in a target selective manner. This review will focus on the role of TGF-beta in T cell differentiation and discuss the prospect of TGF-beta as the therapeutic target of lung transplantation acceptance.
Journal Title: Future medicinal chemistry
Volume: 5
Issue: 3
ISSN: 1756-8927; 1756-8919
Publisher: Unknown  
Journal Place: England
Date Published: 2013
Start Page: 281
End Page: 289
Language: eng
DOI/URL:

10.4155/fmc.12.215

10.4155/fmc.12.215
Notes: ID: 12991; JID: 101511162; ppublish