Pseudoangiomatous stromal hyperplasia (PASH) of the breast: a clinicopathological study of 79 cases. Journal Article

Local Library Link: Find It @ Loyola

Authors: Drinka, E. K.; Bargaje, A.; Ersahin, C. H.; Patel, P; Salhadar, A.; Sinacore, J; Rajan, P.
Article Title: Pseudoangiomatous stromal hyperplasia (PASH) of the breast: a clinicopathological study of 79 cases.
Abstract: BACKGROUND: Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign lesion that can present as a palpable nodule or as an incidental finding in breast biopsies. DESIGN: The study comprised 79 cases diagnosed at Loyola University Medical Center from 2002 to 2009. The pathology slides were reviewed to document the distribution, type, and association with preneoplastic or neoplastic epithelial lesions. Z-test for independent proportions is used for analysis. RESULTS: A total of 76 patients were female and 3 were male. In all, 59.8% of patients presented with a breast mass and in 40.2% the lesion was an incidental finding. Classical PASH morphology was seen in 97.6% and proliferative PASH in 2.4%. Associated epithelial lesions were benign proliferative changes in 60.4%, atypical ductal and atypical lobular hyperplasia in 25.6% and infiltrating carcinoma in 11% of cases. CONCLUSIONS: Based on these results, extensive sampling of biopsy specimen with PASH and appropriate clinical and radiologic follow-up is recommended.
Journal Title: International Journal of Surgical Pathology
Volume: 20
Issue: 1
ISSN: 1940-2465
Publisher: Unknown  
Journal Place: United States
Date Published: 2012
Start Page: 54
End Page: 58
Language: English
DOI/URL:

http://ovidsp.ovid.com/ovidweb.cgi?T=JS=Y=N=fulltext=medl=21862488

http://hn9yf5lh6v.search.serialssolutions.com/?url_ver=Z39.88-2004=info:ofi/fmt:kev:mtx:journal=info:sid/Ovid:medl=article=info:doi/=info:pmid/21862488=1066-8969=20=1=54=54-8=2012=International+Journal+of+Surgical+Pathology=Pseudoangiomatous+stromal+hyperplasia+%28PASH%29+of+the+breast%3A+a+clinicopathological+study+of+79+cases.=Drinka
Notes: ID: 12441; Record Owner: From MEDLINE, a database of the U.S. National Library of Medicine.; Status: MEDLINE; Publishing Model: Journal available in: Print-Electronic Citation processed from: Internet; NLM Journal Code: d4a, 9314927; Electronic Date of Publication: 20110823; Entry Date: 20120723