DNA viral infections complicating lung transplantation Journal Article


Authors: Clark, N. M.; Lynch, J. P., 3rd; Sayah, D.; Belperio, J. A.; Fishbein, M. C.; Weigt, S. S.
Article Title: DNA viral infections complicating lung transplantation
Abstract: DNA viruses with potential to cause complications after lung transplantation include the human Herpesviridae family consisting of cytomegalovirus (CMV), herpes simplex virus 1 and 2 (HSV-1, -2), varicella-zoster virus (VZV), human herpesvirus 6, 7, and 8 (HHV-6, -7, -8), and Epstein-Barr virus (EBV); the Polyomaviridae family consisting of BK virus and JC virus; and the Adenoviridae family consisting of more than 50 adenovirus subtypes. This is a diverse group of viruses with equally diverse immediate and long-term impacts on allograft function and clinical outcomes following lung transplantation. This article discusses the individual pathogens, their epidemiology and clinical manifestations, as well as treatment and preventive strategies in this era of antiviral treatment regimens.
Journal Title: Seminars in respiratory and critical care medicine
Volume: 34
Issue: 3
ISSN: 1098-9048; 1069-3424
Publisher: Unknown  
Journal Place: United States
Date Published: 2013
Start Page: 380
End Page: 404
Language: eng
DOI/URL:
Notes: CI: Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001; JID: 9431858; 2013/07/02 [epublish]; ppublish