Oral alveolar soft part sarcoma in childhood and adolescence: report of two cases and review of literature Journal Article


Authors: Argyris, P. P.; Reed, R. C.; Manivel, J. C.; Lopez-Terrada, D.; Jakacky, J.; Cayci, Z.; Tosios, K. I.; Pambuccian, S. E.; Thompson, L. D.; Koutlas, I. G.
Article Title: Oral alveolar soft part sarcoma in childhood and adolescence: report of two cases and review of literature
Abstract: Alveolar soft part sarcoma (ASPS) constitutes a rare soft tissue malignant neoplasm comprising less than 1 % of all soft tissue sarcomas. ASPS demonstrates a strong predilection for adolescents and young adults, with a female predominance reported. The head and neck region is the most commonly affected region in pediatric patients with the tongue and orbit affected most commonly. Herein we present the clinical, radiographic, histopathologic, immunohistochemical and molecular features of two examples of ASPS affecting the oral cavity of 4 and 13 year-old boys, along with a focused review of the literature on intraoral ASPS in pediatric patients.
Journal Title: Head and neck pathology
Volume: 7
Issue: 1
ISSN: 1936-0568
Publisher: Unknown  
Journal Place: United States
Date Published: 2013
Start Page: 40
End Page: 49
Language: eng
DOI/URL:
Notes: JID: 101304010; OID: NLM: PMC3597158 [Available on 09/08/13]; PMCR: 2013/09/08 00:00; 2012/05/21 [received]; 2012/08/22 [accepted]; 2012/09/08 [aheadofprint]; ppublish