Authors: | Skinner, AM; Tan, X; Sirbu, BD; Danziger, LH; Gerding, DN; Johnson, S |
Article Title: | A Tapered-Pulsed Fidaxomicin Regimen following Treatment in Patients with Multiple Clostridioides difficile Infection Recurrences. |
Abstract: | We treated 46 patients with multiple recurrent Clostridioides difficile infections (mrCDI) using a tapered-pulsed (T-P) fidaxomicin regimen, the majority of whom failed prior T-P vancomycin treatment. Sustained clinical response rates at 30 and 90 days were 74% (34/46) and 61% (28/46). T-P fidaxomicin shows promise for management of mrCDI. |
Journal Title: | Clinical Infectious Diseases |
ISSN: | 1058-4838 |
Publisher: | Unknown |
Date Published: | 2021 |