Role of Microtubules and Microtubule-Associated Proteins in HIV-1 Infection. Journal Article

Local Library Link: Find It @ Loyola

Authors: Dharan, A; Campbell, EM
Article Title: Role of Microtubules and Microtubule-Associated Proteins in HIV-1 Infection.
Abstract: Recent studies show that human immunodeficiency virus type 1 (HIV-1) can utilize microtubules and their associated proteins to complete key postfusion steps during infection. These include associating with both dynein and kinesin motors, as well as proteins, which enhance infection by altering microtubule dynamics during infection. In this article, we will discuss findings on how dynein and kinesin motors, as well as other microtubule-associated proteins, influence HIV-1 trafficking, viral core uncoating, and nuclear import of the viral ribonucleoprotein (RNP).
Journal Title: Journal of virology
ISSN: 1098-5514; 0022-538X
Publisher: American Society for Microbiology. All Rights Reserved  
Date Published: 2018