Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia Journal Article


Authors: Park, K. K.; Tayebi, B.; Uihlein, L.; Speiser, J; Mir, A.; Gerami, P.; Mancini, A.; Kim, W
Article Title: Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia
Abstract: A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.
Keywords: leukemia cutis; acute lymphoblastic leukemia; chilblains; pernio
Journal Title: Pediatric dermatology
Volume: 35
Issue: 1
ISSN: 1525-1470; 0736-8046
Publisher: Wiley Periodicals, Inc  
Journal Place: United States
Date Published: 2018
Start Page: e74
End Page: e75
Language: eng
DOI/URL:
Notes: LR: 20180122; CI: (c) 2017; JID: 8406799; OTO: NOTNLM; 2017/12/13 06:00 [pubmed]; 2017/12/13 06:00 [medline]; 2017/12/13 06:00 [entrez]; ppublish