Surveillance for hepatocellular carcinoma in a Medicaid cirrhotic population Journal Article


Authors: Palmer, L. B.; Kappelman, M. D.; Sandler, R. S.; Hayashi, P. H.
Article Title: Surveillance for hepatocellular carcinoma in a Medicaid cirrhotic population
Abstract: GOALS: To estimate the hepatocellular carcinoma surveillance in the Medicaid cirrhotic population. BACKGROUND: Most studies predate 2005 American Association for the Study of Liver Diseases surveillance recommendations and do not examine the primary target population, cirrhotics. STUDY: From 2006 to 2007, we identified adults with at least 1 cirrhosis International Classification of Disease code and 15 months of continuous enrollment in North Carolina Medicaid, recording claims for abdominal ultrasound, computed tomography, magnetic resonance imaging, and alpha-fetoprotein testing. We used multivariable logistic regression to identify factors independently associated with imaging. RESULTS: A total of 5061 subjects were identified: mean age 54 years, 54% male patients, 35% African American, 56% white. Cirrhosis risk factors were alcohol (59%), hepatitis C (30%), hepatitis B (4%), others (18%), and unknown (24%). Only 26% underwent at least 1 imaging test. Just 12% of those not hospitalized or seen in an emergency department underwent any imaging test. Care in an academic facility, younger age, female sex, viral hepatitis, and Medicare coinsurance were positively associated with imaging. Twenty-one percent saw a gastroenterologist, which increased the odds of undergoing imaging (odds ratio, 2.81; 95% confidence interval, 2.32-3.41), whereas primary care visits did not (odds ratio, 0.94; 95% confidence interval, 0.76-1.16). CONCLUSIONS: Only a quarter of North Carolina Medicaid cirrhotics underwent abdominal imaging over a 15-month period, and many tests may have been conducted without surveillance intent. Gastroenterology visits nearly tripled the odds of imaging, but primary-care visits had no effect. Efforts to improve surveillance rates in cirrhotic patients should target primary care and increased access to subspecialty care.
Journal Title: Journal of clinical gastroenterology
Volume: 47
Issue: 8
ISSN: 1539-2031; 0192-0790
Publisher: Unknown  
Journal Place: United States
Date Published: 2013
Start Page: 713
End Page: 718
Language: eng
DOI/URL:
Notes: LR: 20150909; GR: 5-T32 DK007634/DK/NIDDK NIH HHS/United States; GR: KL2 RR025746/RR/NCRR NIH HHS/United States; GR: KL2 RR025746/RR/NCRR NIH HHS/United States; GR: P30 DK034987/DK/NIDDK NIH HHS/United States; GR: P30 DK034987/DK/NIDDK NIH HHS/United States; GR: T32 DK007634/DK/NIDDK NIH HHS/United States; JID: 7910017; NIHMS444379; OID: NLM: NIHMS444379; OID: NLM: PMC3745802; ppublish