Comparison of flowrates and voided volumes during non-instrumented uroflowmetry and pressure-flow studies in women with stress incontinence Journal Article

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Authors: Mueller, E. R.; Litman, H.; Rickey, L. R.; Sirls, L; Norton, P.; Wilson, T.; Moalli, P.; Albo, M.; Zimmern, P
Article Title: Comparison of flowrates and voided volumes during non-instrumented uroflowmetry and pressure-flow studies in women with stress incontinence
Abstract: AIMS: The Blaivas-Groutz nomogram defines voiding obstruction in women using Qmax from the NIF and the maximum detrusor pressure (Pdetmax ) from the PFS. The aim of this study was to understand the relationship between NIF and PFS maximum flow rates in women with stress incontinence. METHODS: We analyzed the UDS of 597 women with stress-dominant urinary incontinence. Each subject underwent a NIF and then a PFS. Mixed model was used to test the hypothesis that the relationship between flow rates and voided volume (VV) were similar for NIF and PFS. RESULTS: There were 452 subjects with both NIF and PFS studies that met the inclusion criteria and had max flow rate (Qmax ) for both NIF and PFS. The mean age was 53. Overall, higher VV were observed during PFS compared to NIF and subjects had higher Qmax with NIF compared to PFS. The relationship between Qmax and VV was significantly different between NIF and PFS (P 0.004). At 200 ml, NIF Qmax was 14% higher than PFS Qmax and this difference increased to 30% at 700 ml. CONCLUSION: The difference between PFS Qmax and NIF Qmax increases as VV increase. As a result, values from PFS and NIF cannot be used interchangeably as has been suggested in the Blaivas-Groutz nomogram for obstruction in women.
Journal Title: Neurourology and urodynamics
Volume: 34
Issue: 6
ISSN: 1520-6777; 0733-2467
Publisher: Wiley Periodicals, Inc  
Journal Place: United States
Date Published: 2015
Start Page: 549
End Page: 553
Language: eng
DOI/URL:

10.1002/nau.22625
Notes: LR: 20150801; CI: (c) 2014; GR: U01 DK058225/DK/NIDDK NIH HHS/United States; GR: U01 DK058229/DK/NIDDK NIH HHS/United States; GR: U01 DK058231/DK/NIDDK NIH HHS/United States; GR: U01 DK058234/DK/NIDDK NIH HHS/United States; GR: U01 DK060379/DK/NIDDK NIH HHS/United States; GR: U01 DK060380/DK/NIDDK NIH HHS/United States; GR: U01 DK060393/DK/NIDDK NIH HHS/United States; GR: U01 DK060395/DK/NIDDK NIH HHS/United States; GR: U01 DK060397/DK/NIDDK NIH HHS/United States; GR: U01 DK060401/DK/NIDDK NIH HHS/United States; GR: U01DK58225/DK/NIDDK NIH HHS/United States; GR: U01DK58229/DK/NIDDK NIH HHS/United States; GR: U01DK58231/DK/NIDDK NIH HHS/United States; GR: U01DK58234/DK/NIDDK NIH HHS/United States; GR: U01DK60379/DK/NIDDK NIH HHS/United States; GR: U01DK60380/DK/NIDDK NIH HHS/United States; GR: U01DK60393/DK/NIDDK NIH HHS/United States; GR: U01DK60395/DK/NIDDK NIH HHS/United States; GR: U01DK60397/DK/NIDDK NIH HHS/United States; GR: U01DK60401/DK/NIDDK NIH HHS/United States; JID: 8303326; NIHMS592545; OID: NLM: NIHMS592545; OID: NLM: PMC4219932; OTO: NOTNLM; 2013/11/22 [received]; 2014/04/03 [accepted]; 2014/05/04 [aheadofprint]; ppublish