Light-emitting Diodes: A Brief Review and Clinical Experience Journal Article

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Authors: Opel, D. R.; Hagstrom, E.; Pace, A. K.; Sisto, K.; Hirano-Ali, S. A.; Desai, S; Swan, J
Article Title: Light-emitting Diodes: A Brief Review and Clinical Experience
Abstract: BACKGROUND: In the early 1990s, the biological significance of light-emitting diodes was realized. Since this discovery, various light sources have been investigated for their cutaneous effects. STUDY DESIGN: A Medline search was performed on light-emitting diode lights and their therapeutic effects between 1996 and 2010. Additionally, an open-label, investigator-blinded study was performed using a yellow light-emitting diode device to treat acne, rosacea, photoaging, alopecia areata, and androgenetic alopecia. RESULTS: The authors identified several case-based reports, small case series, and a few randomized controlled trials evaluating the use of four different wavelengths of light-emitting diodes. These devices were classified as red, blue, yellow, or infrared, and covered a wide range of clinical applications. The 21 patients the authors treated had mixed results regarding patient satisfaction and pre- and post-treatment evaluation of improvement in clinical appearance. CONCLUSION: Review of the literature revealed that differing wavelengths of light-emitting diode devices have many beneficial effects, including wound healing, acne treatment, sunburn prevention, phototherapy for facial rhytides, and skin rejuvenation. The authors' clinical experience with a specific yellow light-emitting diode device was mixed, depending on the condition being treated, and was likely influenced by the device parameters.
Journal Title: The Journal of clinical and aesthetic dermatology
Volume: 8
Issue: 6
ISSN: 1941-2789; 1941-2789
Publisher: Unknown  
Journal Place: United States
Date Published: 2015
Start Page: 36
End Page: 44
Language: eng
Notes: LR: 20150711; JID: 101518173; OID: NLM: PMC4479368; ppublish