Prediction of fracture risk in patients with osteoporosis: a brief review Journal Article

Local Library Link: Find It @ Loyola

Authors: Arceo-Mendoza, R. M.; Camacho, P
Article Title: Prediction of fracture risk in patients with osteoporosis: a brief review
Abstract: Osteoporosis, a well-defined and growing public health problem, is a disease characterized by increased bone turnover and decreased bone mass with associated skeletal fragility, resulting in an increased risk of fracture. It is often unrecognized until the late stages when fragility fractures have occurred. In adults, early recognition of the disease prior to the occurrence of fractures followed by timely and efficient initiation of appropriate treatment can reduce fracture risk. In this article, we review clinical modalities available to effectively predict fracture risk in patients with osteoporosis. Bone mineral density and presence of clinical risk factors may be combined to provide a more comprehensive osteoporotic fracture risk assessment. Use of FRAX may serve as a general guideline for clinical management and deciding a threshold for cost-effective pharmacological intervention. Elevated bone turnover markers are predictive of high fracture risk and can provide additional clinical information as well.
Journal Title: Women's health (London, England)
ISSN: 1745-5065; 1745-5057
Publisher: Unknown  
Date Published: 2015
Start Page: 1
End Page: 8
Language: ENG
DOI/URL:

10.2217/whe.15.14
Notes: LR: 20150804; JID: 101271249; OTO: NOTNLM; aheadofprint; SO: Womens Health (Lond Engl). 2015 Aug 3:1-8.
LUC Authors
  1. Pauline Camacho
    24 Camacho
Related LUC Article