Self-reported memory problems in adult-onset cancer survivors: effects of cardiovascular disease and insomnia Journal Article

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Authors: Jean-Pierre, P.; Grandner, M. A.; Garland, S. N.; Henry, E; Jean-Louis, G; Burish, T. G.
Article Title: Self-reported memory problems in adult-onset cancer survivors: effects of cardiovascular disease and insomnia
Abstract: BACKGROUND: Cancer and its treatments can deleteriously affect memory. Cardiac function and insomnia can exacerbate memory problems. OBJECTIVE: To examine the relationships among cardiovascular disease, insomnia, and self-reported memory problems (SRMP) in adult-onset cancer survivors. METHODS: We included data from participants (41-64 year-old) of the 2007-2008 National Health and Nutrition Examination Survey, a nationally representative probability sample of the civilian, non-institutionalized population of the US. We excluded participants with brain cancer/stroke history since these conditions are expected to cause cognitive problems. Using binary logistic regression, we determined the prevalence of SRMP relative to cardiac problems and insomnia by weighting our results proportionally. We adjusted for predictors of memory problems: age, sex, race, education and general health. RESULTS: The sample included 2289 adults (49% females), 9% with a cancer history. The results pertain only to cancer survivors. Those with insomnia were 16 times as likely to have SRMP. Only insomnia symptoms (OR, 15.74; 95% CI, 1.73-143.30; p 0.05). LIMITATIONS: We could not determine severity and time-related changes in SRMP. CONCLUSION: Likelihood of SRMP was higher in cancer survivors with a history of cardiovascular disease and insomnia symptoms. Future studies are needed to delineate the cardiac-insomnia-memory interrelationships.
Journal Title: Sleep medicine
Volume: 16
Issue: 7
ISSN: 1878-5506; 1389-9457
Publisher: Elsevier Inc  
Journal Place: Netherlands
Date Published: 2015
Start Page: 845
End Page: 849
Language: eng
DOI/URL:

10.1016/j.sleep.2015.02.531
Notes: LR: 20150615; CI: Copyright (c) 2015; GR: KL2 TR000163/TR/NCATS NIH HHS/United States; GR: L60 MD001957/MD/NIMHD NIH HHS/United States; JID: 100898759; NIHMS673507; OTO: NOTNLM; PMCR: 2016/07/01 00:00; 2014/05/30 [received]; 2015/02/06 [revised]; 2015/02/17 [accepted]; 2015/03/18 [aheadofprint]; ppublish