Blood alcohol content, injury severity, and adult respiratory distress syndrome Journal Article


Authors: Afshar, M; Smith, G. S.; Terrin, M. L.; Barrett, M.; Lissauer, M. E.; Mansoor, S.; Jeudy, J.; Netzer, G
Article Title: Blood alcohol content, injury severity, and adult respiratory distress syndrome
Abstract: BACKGROUND: Elevated blood alcohol content (BAC) is a risk factor for injury. Associations of BAC with adult respiratory distress syndrome (ARDS) have not been conclusively established.We evaluated the association of a BAC greater than 0 mg/dL with the intermediate outcomes, Injury Severity Score (ISS) and Glasgow Coma Scale (GCS) score, and their association with ARDS development. METHODS: This is an observational retrospective cohort study of 26,305 primary trauma admissions to a statewide referral trauma center from July 11, 2003, to October 31, 2011. Logistic regression was performed to assess the relationship between admission BAC, ISS, GCS score, and ARDS development within 5 days of admission. RESULTS: The case rate for ARDS was 5.5% (1,447). BAC greater than 0 mg/dL was associated with ARDS development in adjusted analysis (odds ratio, 1.50; 95% confidence interval [CI], 1.33-1.71; p /=16) had a stronger association with ARDS development (odds ratio, 17.99; 95% CI, 15.51-20.86), as did low GCS score (
Keywords: Adult; Female; Humans; Middle Aged; Young Adult; Injury Severity Score; Male; Retrospective Studies; Risk Factors; Follow-Up Studies; Incidence; Time Factors; Confidence Intervals; Odds Ratio; Trauma Centers/statistics numerical data; Alcohol Drinking/adverse effects/blood; Ethanol/pharmacokinetics; Maryland/epidemiology; Respiratory Distress Syndrome, Adult/blood/epidemiology/etiology; Survival Rate/trends; Wounds and Injuries/blood/complications
Journal Title: The journal of trauma and acute care surgery
Volume: 76
Issue: 6
ISSN: 2163-0763; 2163-0755
Publisher: Unknown  
Date Published: 2014
Start Page: 1447
End Page: 1455
LUC Authors
  1. Majid Afshar
    61 Afshar
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