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Predictors of non-compliance in autologous hematopoietic SCT patients undergoing out-patient transplants. Journal Article
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| Authors: | Mumby, P. B.; Hurley, C.; Samsi, M.; Thilges, S.; Parthasarathy, M.; Stiff, P. J. |
| Article Title: | Predictors of non-compliance in autologous hematopoietic SCT patients undergoing out-patient transplants. |
| Abstract: | Non-compliance has received significant attention in medicine, yet few studies have examined its correlates in autologous hematopoietic SCT (AHSCT) patients. This study examined predictors of non-compliance in a sample of 151 AHSCT patients treated in an outpatient setting. Before AHSCT, participants completed a validated measure of mood and retrospective chart reviews were conducted to assess non-compliance during AHSCT, defined as refusal of oral hygiene, prescribed exercise programs, oral nutrition and/or prescribed medications. We found 121 patients (80%) were non-compliant with an aspect of the AHSCT regimen on 1 or more days; mean percentage of non-compliant days was 16.6 (s.d. 15.6). Men were more likely than women to be non-compliant (P0.05); as were participants with an elevated depression score (P0.05). Stepwise regression models identified significant predictors of non-compliance: gender, depression, global distress and nausea and vomiting severity (P-values all 0.01). Further analysis revealed that the interaction of the psychological variables with gender was a more robust predictor of non-compliance (P0.001). For outpatient AHSCT, our findings suggest the need to broaden conceptualizations of risk factors for non-compliance and the importance of assessing patient barriers to compliance to ensure optimal treatment outcome. |
| Journal Title: | Bone marrow transplantation |
| Volume: | 47 |
| Issue: | 4 |
| ISSN: | 1476-5365; 0268-3369 |
| Publisher: | Unknown |
| Journal Place: | England |
| Date Published: | 2012 |
| Start Page: | 556 |
| End Page: | 561 |
| Language: | English |
| DOI/URL: | |
| Notes: | ID: 12439; Record Owner: From MEDLINE, a database of the U.S. National Library of Medicine.; Status: MEDLINE; Publishing Model: Journal available in: Print-Electronic Citation processed from: Internet; NLM Journal Code: bon, 8702459; Electronic Date of Publication: 20110620; Entry Date: 20120730 |
