Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference Journal Article


Authors: Ezzedine, K.; Lim, H. W.; Suzuki, T.; Katayama, I.; Hamzavi, I.; Lan, C. C.; Goh, B. K.; Anbar, T.; Silva de Castro, C.; Lee, A. Y.; Parsad, D.; van Geel, N.; Le Poole, I. C.; Oiso, N.; Benzekri, L.; Spritz, R.; Gauthier, Y.; Hann, S. K.; Picardo, M.; Taieb, A.; Vitiligo Global Issue Consensus Conference Panelists
Article Title: Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference
Abstract: During the 2011 International Pigment Cell Conference (IPCC), the Vitiligo European Taskforce (VETF) convened a consensus conference on issues of global importance for vitiligo clinical research. As suggested by an international panel of experts, the conference focused on four topics: classification and nomenclature; definition of stable disease; definition of Koebner's phenomenon (KP); and 'autoimmune vitiligo'. These topics were discussed in seven working groups representing different geographical regions. A consensus emerged that segmental vitiligo be classified separately from all other forms of vitiligo and that the term 'vitiligo' be used as an umbrella term for all non-segmental forms of vitiligo, including 'mixed vitiligo' in which segmental and non-segmental vitiligo are combined and which is considered a subgroup of vitiligo. Further, the conference recommends that disease stability be best assessed based on the stability of individual lesions rather than the overall stability of the disease as the latter is difficult to define precisely and reliably. The conference also endorsed the classification of KP for vitiligo as proposed by the VETF (history based, clinical observation based, or experimentally induced). Lastly, the conference agreed that 'autoimmune vitiligo' should not be used as a separate classification as published evidence indicates that the pathophysiology of all forms of vitiligo likely involves autoimmune or inflammatory mechanisms.
Keywords: Humans; Pathology; Terminology as Topic; Autoimmune Diseases/classification/complications/diagnosis/etiology; Congresses as Topic/organization administration; Consensus; Disease Progression; International Cooperation; Vitiligo/classification/complications/diagnosis/etiology
Journal Title: Pigment cell melanoma research
Volume: 25
Issue: 3
ISSN: 1755-148X; 1755-1471
Publisher: Wiley Periodicals, Inc  
Journal Place: England
Date Published: 2012
Start Page: E1
End Page: 13
Language: eng
DOI/URL:
Notes: LR: 20130626; CI: (c) 2012; GR: R01 AR045584/AR/NIAMS NIH HHS/United States; GR: R01 AR056292/AR/NIAMS NIH HHS/United States; JID: 101318927; NIHMS422674; OID: NLM: NIHMS422674; OID: NLM: PMC3511780; ppublish