Endoluminal revision of gastric bypass for weight regain--a systematic review Journal Article

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Authors: Dakin, G. F.; Eid, G.; Mikami, D; Pryor, A.; Chand, B; American Society for Metabolic and Bariatric Surgery (ASMBS) Emerging Technology and Procedures Committee
Article Title: Endoluminal revision of gastric bypass for weight regain--a systematic review
Abstract: BACKGROUND: Weight recidivism after Roux-en-Y gastric bypass (RYGB) is a challenging problem for patients and bariatric surgeons alike. Traditional operative strategies to combat weight regain are technically challenging and associated with a high morbidity rate. Endoluminal interventions are thus an attractive alternative that may offer a good combination of results coupled with lower periprocedure risk that might one day provide a solution to this increasingly prevalent problem. The purpose of this article is to systematically review the available literature on endoluminal procedures used to address weight regain after RYGB, with specific attention to the safety profile, efficacy, cost, and current availability. This review focuses only on endoluminal procedures that are performed for weight regain after RYGB, as opposed to primary endoluminal obesity procedures. METHODS: This study was a retrospective review. RESULTS: Several methods of endoluminal intervention for weight regain are reviewed, ranging from injection of inert substances to suturing and clipping devices. The literature review shows the procedures on the whole to be well tolerated with limited efficacy. The majority of the literature is limited to small case series. Most of the reviewed devices are no longer commercially available. CONCLUSIONS: Endoluminal therapy represents an intriguing strategy for weight regain after RYGB. However, the current and future technologies must be rigorously studied and improved such that they offer durable, repeatable, cost-effective solutions.
Journal Title: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Volume: 9
Issue: 3
ISSN: 1878-7533; 1550-7289
Publisher: Elsevier Inc  
Journal Place: United States
Date Published: 2013
Start Page: 335
End Page: 342
Language: eng
DOI/URL:

10.1016/j.soard.2013.03.001

10.1016/j.soard.2013.03.001
Notes: CI: Copyright (c) 2013; JID: 101233161; CIN: Surg Obes Relat Dis. 2013 May-Jun;9(3):342-3. PMID: 23602495; 2013/01/24 [received]; 2013/01/29 [revised]; 2013/03/01 [accepted]; 2013/03/07 [aheadofprint]; ppublish