Late complications after pancreaticoduodenectomy with pancreaticogastrostomy. Journal Article

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Authors: Bock, E. A.; Hurtuk, M. G.; Shoup, M.; Aranha, G. V.
Article Title: Late complications after pancreaticoduodenectomy with pancreaticogastrostomy.
Abstract: INTRODUCTION: We investigated complications after pancreaticoduodenectomy (PD) with pancreaticogastrostomy (PG) reconstruction more than 12[NON-BREAKING SPACE]months postoperatively. METHODS: Through chart review and outpatient follow-up, we assessed the incidence of new-onset diabetes mellitus (DM) and steatorrhea after PD. RESULTS: Ninety patients underwent PD with PG with a median follow-up of 4.7[NON-BREAKING SPACE]years (range 0.4-15.8[NON-BREAKING SPACE]years). Of the 77 patients without DM preoperatively, 18 (23.4%) developed DM postoperatively. Those who developed DM were younger at time of surgery than those who did not (60.5 versus 65.8[NON-BREAKING SPACE]years; p[THIN SPACE]=[THIN SPACE]0.021), but postoperative survival did not differ between these groups. The incidence of DM was comparable to the incidence of DM in the general population. Out of 89 patients, 47 (52.8%) now require pancreatic enzyme therapy. The group that developed steatorrhea underwent PD at a younger age (61.4 versus 67.0[NON-BREAKING SPACE]years; p[THIN SPACE]=[THIN SPACE]0.029). CONCLUSIONS: Patients that undergo PD at a younger age are more likely to develop DM and steatorrhea than their older counterparts; patients are as likely as the general population, however, to develop DM after PD with PG.
Journal Title: Journal of Gastrointestinal Surgery
Volume: 16
Issue: 5
ISSN: 1873-4626
Publisher: Unknown  
Journal Place: United States
Date Published: 2012
Start Page: 914
End Page: 919
Language: English
DOI/URL:

http://ovidsp.ovid.com/ovidweb.cgi?T=JS=Y=N=fulltext=medl=22374385

http://hn9yf5lh6v.search.serialssolutions.com/?url_ver=Z39.88-2004=info:ofi/fmt:kev:mtx:journal=info:sid/Ovid:medl=article=info:doi/=info:pmid/22374385=1091-255X=16=5=914=914-9=2012=Journal+of+Gastrointestinal+Surgery=Late+complications+after+pancreaticoduodenectomy+with+pancreaticogastrostomy.=Bock
Notes: ID: 12463; Record Owner: From MEDLINE, a database of the U.S. National Library of Medicine.; Status: MEDLINE; Publishing Model: Journal available in: Print-Electronic Citation processed from: Internet; NLM Journal Code: 9706084, c7y; Electronic Date of Publication: 20120229; Entry Date: 20120827