Commonly asked questions: thrombolytic therapy in the management of acute stroke Journal Article

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Authors: Block, H. S.; Biller, J
Article Title: Commonly asked questions: thrombolytic therapy in the management of acute stroke
Abstract: Questions about thrombolytic management arise frequently, often with the intent of ascertaining safety and efficacy in specific situations. Thrombolytic therapy is generally safe, even if a nonruptured intracranial aneurysm is present. The risk of cardiac rupture with tamponade is low, except for the first 7 weeks following myocardial infarction. Over this duration, there is an increased risk of intravenous thrombolytic therapy in specific patient groups. Stroke infrequently occurs during cardiac catheterization. Its infrequent occurrence has limited large treatment trials. Basilar artery occlusion management will be reviewed. Thrombolytic therapy is generally safe in the context of pre-existing cerebral microhemorrhages and cervical artery dissections. Additionally, the role of multimodal penumbral imaging in planning stroke therapy will be reviewed.
Journal Title: Expert Review of Neurotherapeutics
Volume: 13
Issue: 2
ISSN: 1744-8360
Publisher: Unknown  
Journal Place: England
Date Published: 2013
Start Page: 157
End Page: 165
Language: eng
DOI/URL:

10.1586/ern.12.163

10.1586/ern.12.163
Notes: ID: 13052; JID: 101129944; ppublish